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miR-497 suppresses epithelial–mesenchymal transition and metastasis in colorectal cancer cells by targeting fos-related antigen-1

OBJECTIVE: MicroRNAs have key roles in tumor metastasis. The acquisition of metastatic capability by cancer cells is associated with epithelial–mesenchymal transition (EMT). Here, we describe the role and molecular mechanism of miR-497 in colorectal cancer (CRC) cell EMT, migration, and invasion. ME...

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Shen, Quan, Zhang, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087769/
https://www.ncbi.nlm.nih.gov/pubmed/27822064
http://dx.doi.org/10.2147/OTT.S114609