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Ursolic acid sensitizes cisplatin-resistant HepG2/DDP cells to cisplatin via inhibiting Nrf2/ARE pathway

BACKGROUND: Combinations of adjuvant sensitizers with anticancer drugs is a promising new strategy to reverse chemoresistance. Ursolic acid (UA) is one of the natural pentacyclic triterpene compounds known to have many pharmacological characteristics such as anti-inflammatory and anticancer properti...

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Detalles Bibliográficos
Autores principales: Wu, Shouhai, Zhang, Tianpeng, Du, Jingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087784/
https://www.ncbi.nlm.nih.gov/pubmed/27822011
http://dx.doi.org/10.2147/DDDT.S110505