Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology

Osteocalcin, also known as bone γ-carboxyglutamate protein (Bglap), is expressed by osteoblasts and is commonly used as a clinical marker of bone turnover. A mouse model of osteocalcin deficiency has implicated osteocalcin as a mediator of changes to the skeleton, endocrine system, reproductive orga...

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Detalles Bibliográficos
Autores principales: Lambert, Laura J., Challa, Anil K., Niu, Aidi, Zhou, Lihua, Tucholski, Janusz, Johnson, Maria S., Nagy, Tim R., Eberhardt, Alan W., Estep, Patrick N., Kesterson, Robert A., Grams, Jayleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087831/
https://www.ncbi.nlm.nih.gov/pubmed/27483347
http://dx.doi.org/10.1242/dmm.025247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087831/
https://www.ncbi.nlm.nih.gov/pubmed/27483347
http://dx.doi.org/10.1242/dmm.025247

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