Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury

Hemoglobin-vesicles (HbV), encapsulating highly concentrated human hemoglobin in liposomes, were developed as a substitute for red blood cells (RBC) and their safety and efficacy in transfusion therapy has been confirmed in previous studies. Although HbV suspensions are structurally and physicochemi...

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Detalles Bibliográficos
Autores principales: Tokuno, Masahiro, Taguchi, Kazuaki, Yamasaki, Keishi, Sakai, Hiromi, Otagiri, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087860/
https://www.ncbi.nlm.nih.gov/pubmed/27798697
http://dx.doi.org/10.1371/journal.pone.0165557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087860/
https://www.ncbi.nlm.nih.gov/pubmed/27798697
http://dx.doi.org/10.1371/journal.pone.0165557

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