Platform-Independent Genome-Wide Pattern of DNA Copy-Number Alterations Predicting Astrocytoma Survival and Response to Treatment Revealed by the GSVD Formulated as a Comparative Spectral Decomposition

We use the generalized singular value decomposition (GSVD), formulated as a comparative spectral decomposition, to model patient-matched grades III and II, i.e., lower-grade astrocytoma (LGA) brain tumor and normal DNA copy-number profiles. A genome-wide tumor-exclusive pattern of DNA copy-number al...

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Detalles Bibliográficos
Autores principales: Aiello, Katherine A., Alter, Orly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087864/
https://www.ncbi.nlm.nih.gov/pubmed/27798635
http://dx.doi.org/10.1371/journal.pone.0164546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087864/
https://www.ncbi.nlm.nih.gov/pubmed/27798635
http://dx.doi.org/10.1371/journal.pone.0164546

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