Application of High-Throughput Next-Generation Sequencing for HLA Typing on Buccal Extracted DNA: Results from over 10,000 Donor Recruitment Samples

BACKGROUND: Unambiguous HLA typing is important in hematopoietic stem cell transplantation (HSCT), HLA disease association studies, and solid organ transplantation. However, current molecular typing methods only interrogate the antigen recognition site (ARS) of HLA genes, resulting in many cis-trans...

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Detalles Bibliográficos
Autores principales: Yin, Yuxin, Lan, James H., Nguyen, David, Valenzuela, Nicole, Takemura, Ping, Bolon, Yung-Tsi, Springer, Brianna, Saito, Katsuyuki, Zheng, Ying, Hague, Tim, Pasztor, Agnes, Horvath, Gyorgy, Rigo, Krisztina, Reed, Elaine F., Zhang, Qiuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087893/
https://www.ncbi.nlm.nih.gov/pubmed/27798706
http://dx.doi.org/10.1371/journal.pone.0165810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087893/
https://www.ncbi.nlm.nih.gov/pubmed/27798706
http://dx.doi.org/10.1371/journal.pone.0165810

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