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A Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo

Neuropilin-1 (NRP1) is a transmembrane protein acting as a co-receptor for several growth factors and interacting with other proteins such as integrins and plexins/semaphorins. It is involved in axonal development, angiogenesis and cancer progression. Its primary mRNA is subjected to alternative spl...

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Detalles Bibliográficos
Autores principales: Hendricks, Céline, Dubail, Johanne, Brohée, Laura, Delforge, Yves, Colige, Alain, Deroanne, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087894/
https://www.ncbi.nlm.nih.gov/pubmed/27798666
http://dx.doi.org/10.1371/journal.pone.0165153