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Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription

DNA breaks activate the DNA damage response and, if left unrepaired, trigger cellular senescence. Telomeres are specialized nucleoprotein structures that protect chromosome ends from persistent DNA damage response activation. Whether protection can be enhanced to counteract the age-dependent decline...

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Detalles Bibliográficos
Autores principales: Diman, Aurélie, Boros, Joanna, Poulain, Florian, Rodriguez, Julie, Purnelle, Marin, Episkopou, Harikleia, Bertrand, Luc, Francaux, Marc, Deldicque, Louise, Decottignies, Anabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087959/
https://www.ncbi.nlm.nih.gov/pubmed/27819056
http://dx.doi.org/10.1126/sciadv.1600031