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Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription
DNA breaks activate the DNA damage response and, if left unrepaired, trigger cellular senescence. Telomeres are specialized nucleoprotein structures that protect chromosome ends from persistent DNA damage response activation. Whether protection can be enhanced to counteract the age-dependent decline...
Autores principales: | Diman, Aurélie, Boros, Joanna, Poulain, Florian, Rodriguez, Julie, Purnelle, Marin, Episkopou, Harikleia, Bertrand, Luc, Francaux, Marc, Deldicque, Louise, Decottignies, Anabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087959/ https://www.ncbi.nlm.nih.gov/pubmed/27819056 http://dx.doi.org/10.1126/sciadv.1600031 |
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