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Aberrant Expression of Histone Deacetylases 4 in Cognitive Disorders: Molecular Mechanisms and a Potential Target

Histone acetylation is a major mechanism of chromatin remodeling, contributing to epigenetic regulation of gene transcription. Histone deacetylases (HDACs) are involved in both physiological and pathological conditions by regulating the status of histone acetylation. Although histone deacetylase 4 (...

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Detalles Bibliográficos
Autores principales: Wu, Yili, Hou, Fei, Wang, Xin, Kong, Qingsheng, Han, Xiaolin, Bai, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088184/
https://www.ncbi.nlm.nih.gov/pubmed/27847464
http://dx.doi.org/10.3389/fnmol.2016.00114