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GluN2A Subunit-Containing NMDA Receptors Are the Preferential Neuronal Targets of Homocysteine

Homocysteine (HCY) is an endogenous redox active amino acid, best known as contributor to various neurodegenerative disorders. Although it is known that HCY can activate NMDA receptors (NMDARs), the mechanisms of its action on receptors composed of different NMDA receptor subunits remains almost unk...

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Detalles Bibliográficos
Autores principales: Sibarov, Dmitry A., Abushik, Polina A., Giniatullin, Rashid, Antonov, Sergei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088185/
https://www.ncbi.nlm.nih.gov/pubmed/27847466
http://dx.doi.org/10.3389/fncel.2016.00246