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Combination Approaches with Immune-Checkpoint Blockade in Cancer Therapy

In healthy individuals, immune-checkpoint molecules prevent autoimmune responses and limit immune cell-mediated tissue damage. Tumors frequently exploit these molecules to evade eradication by the immune system. Over the past years, immune-checkpoint blockade of cytotoxic T lymphocyte antigen-4 and...

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Detalles Bibliográficos
Autores principales: Swart, Maarten, Verbrugge, Inge, Beltman, Joost B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088186/
https://www.ncbi.nlm.nih.gov/pubmed/27847783
http://dx.doi.org/10.3389/fonc.2016.00233