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In-Source Decay and Pseudo-MS(3) of Peptide and Protein Ions Using Liquid AP-MALDI

Atmospheric pressure MALDI on a Q-Exactive instrument was optimized for in-source decay and pseudo-MS(3). The dependence of AP-MALDI ISD on the MALDI liquid matrix was investigated for peptides and proteins. The liquid matrices enabled long-life ISD signal, and exhibited high fragment ion yield and...

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Detalles Bibliográficos
Autores principales: Ait-Belkacem, Rima, Dilillo, Marialaura, Pellegrini, Davide, Yadav, Avinash, de Graaf, Erik L., McDonnell, Liam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088222/
https://www.ncbi.nlm.nih.gov/pubmed/27752913
http://dx.doi.org/10.1007/s13361-016-1511-0