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Members of the Cyr61/CTGF/NOV Protein Family: Emerging Players in Hepatic Progenitor Cell Activation and Intrahepatic Cholangiocarcinoma

Hepatic stem/progenitor cells (HPC) reside quiescently in normal biliary trees and are activated in the form of ductular reactions during severe liver damage when the replicative ability of hepatocytes is inhibited. HPC niches are full of profibrotic stimuli favoring scarring and hepatocarcinogenesi...

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Detalles Bibliográficos
Autores principales: Wu, Qunfeng, Jorgensen, Marda, Song, Joanna, Zhou, Junmei, Liu, Chen, Pi, Liya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088274/
https://www.ncbi.nlm.nih.gov/pubmed/27829832
http://dx.doi.org/10.1155/2016/2313850