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Safe dose of intravitreal imatinib and its effect on laser-induced choroidal neovascularization: a rat-model experiment

BACKGROUND: This two-phase experimental study was conducted to determine the maximum safe dose of intravitreal imatinib (IVI) and its inhibitory effect on a rat model of choroidal neovascularization (CNV). METHODS: In phase I, 60 rats were divided into six groups (A to F); five of which received IVI...

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Detalles Bibliográficos
Autores principales: Nikkhah, Homayoun, Ahmadieh, Hamid, Ramezani, Alireza, Rezaei Kanavi, Mozhgan, Hosseini, Seyed Bagher, Sadeghi, Naficeh, Khandaghy Meybodi, Seyed Mohsen, Yaseri, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088484/
https://www.ncbi.nlm.nih.gov/pubmed/27847609
http://dx.doi.org/10.1186/s40942-015-0017-4