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Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex
BACKGROUND: Why we sleep is still one of the most perplexing mysteries in biology. Strong evidence indicates that sleep is necessary for normal brain function and that sleep need is a tightly regulated process. Surprisingly, molecular mechanisms that determine sleep need are incompletely described....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088519/ https://www.ncbi.nlm.nih.gov/pubmed/27801296 http://dx.doi.org/10.1186/s12864-016-3065-8 |