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Spatial focalization of pheromone/MAPK signaling triggers commitment to cell–cell fusion

Cell fusion is universal in eukaryotes for fertilization and development, but what signals this process is unknown. Here, we show in Schizosaccharomyces pombe that fusion does not require a dedicated signal but is triggered by spatial focalization of the same pheromone–GPCR (G-protein-coupled recept...

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Detalles Bibliográficos
Autores principales: Dudin, Omaya, Merlini, Laura, Martin, Sophie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088570/
https://www.ncbi.nlm.nih.gov/pubmed/27798845
http://dx.doi.org/10.1101/gad.286922.116