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Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors

Testicular germ cell tumors (TGCTs) share germline ancestry but diverge phenotypically and clinically as seminoma (SE) and nonseminoma (NSE), the latter including the pluripotent embryonal carcinoma (EC) and its differentiated derivatives, teratoma (TE), yolk sac tumor (YST), and choriocarcinoma. Ep...

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Detalles Bibliográficos
Autores principales: Killian, J. Keith, Dorssers, Lambert C.J., Trabert, Britton, Gillis, Ad J.M., Cook, Michael B., Wang, Yonghong, Waterfall, Joshua J., Stevenson, Holly, Smith, William I., Noyes, Natalia, Retnakumar, Parvathy, Stoop, J. Hans, Oosterhuis, J. Wolter, Meltzer, Paul S., McGlynn, Katherine A., Looijenga, Leendert H.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088592/
https://www.ncbi.nlm.nih.gov/pubmed/27803193
http://dx.doi.org/10.1101/gr.201293.115