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Reconstructed cell fate–regulatory programs in stem cells reveal hierarchies and key factors of neurogenesis
Cell lineages, which shape the body architecture and specify cell functions, derive from the integration of a plethora of cell intrinsic and extrinsic signals. These signals trigger a multiplicity of decisions at several levels to modulate the activity of dynamic gene regulatory networks (GRNs), whi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088593/ https://www.ncbi.nlm.nih.gov/pubmed/27650846 http://dx.doi.org/10.1101/gr.208926.116 |