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Reconstructed cell fate–regulatory programs in stem cells reveal hierarchies and key factors of neurogenesis

Cell lineages, which shape the body architecture and specify cell functions, derive from the integration of a plethora of cell intrinsic and extrinsic signals. These signals trigger a multiplicity of decisions at several levels to modulate the activity of dynamic gene regulatory networks (GRNs), whi...

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Detalles Bibliográficos
Autores principales: Mendoza-Parra, Marco-Antonio, Malysheva, Valeriya, Mohamed Saleem, Mohamed Ashick, Lieb, Michele, Godel, Aurelie, Gronemeyer, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088593/
https://www.ncbi.nlm.nih.gov/pubmed/27650846
http://dx.doi.org/10.1101/gr.208926.116