Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies

Nrf2 (nuclear factor [erythroid-derived 2]-like 2; the transcriptional master regulator of the antioxidant stress response) is regulated through interaction with its cytoplasmic inhibitor Keap1 (Kelch-like ECH-associated protein 1), which under basal conditions targets Nrf2 for proteasomal degrad...

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Detalles Bibliográficos
Autores principales: Duleh, Steve, Wang, Xianhong, Komirenko, Allison, Margeta, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088660/
https://www.ncbi.nlm.nih.gov/pubmed/27799074
http://dx.doi.org/10.1186/s40478-016-0384-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088660/
https://www.ncbi.nlm.nih.gov/pubmed/27799074
http://dx.doi.org/10.1186/s40478-016-0384-6

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