Effects of flavopiridol on critical regulation pathways of CD133(high)/CD44(high) lung cancer stem cells

BACKGROUND: Flavopiridol a semisynthetic flavone that inhibits cyclin-dependent kinases (CDKs) and has growth-inhibitory activity and induces a blockade of cell-cycle progression at G1-phase and apoptosis in numerous human tumor cell lines and is currently under investigation in phase II clinical tr...

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Detalles Bibliográficos
Autores principales: Bozok Cetintas, Vildan, Acikgoz, Eda, Yigitturk, Gurkan, Demir, Kenan, Oktem, Gulperi, Tezcanli Kaymaz, Burçin, Oltulu, Fatih, Aktug, Huseyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089099/
https://www.ncbi.nlm.nih.gov/pubmed/27787370
http://dx.doi.org/10.1097/MD.0000000000005150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089099/
https://www.ncbi.nlm.nih.gov/pubmed/27787370
http://dx.doi.org/10.1097/MD.0000000000005150

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