South-East Asian strains of Plasmodium falciparum display higher ratio of non-synonymous to synonymous polymorphisms compared to African strains

Resistance to frontline anti-malarial drugs, including artemisinin, has repeatedly arisen in South-East Asia, but the reasons for this are not understood. Here we test whether evolutionary constraints on Plasmodium falciparum strains from South-East Asia differ from African strains. We find a signif...

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Detalles Bibliográficos
Autores principales: Singh, Gajinder Pal, Sharma, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089136/
https://www.ncbi.nlm.nih.gov/pubmed/27853513
http://dx.doi.org/10.12688/f1000research.9372.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089136/
https://www.ncbi.nlm.nih.gov/pubmed/27853513
http://dx.doi.org/10.12688/f1000research.9372.2

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