Molecular docking and molecular dynamics simulation study of inositol phosphorylceramide synthase – inhibitor complex in leishmaniasis: Insight into the structure based drug design

Inositol phosphorylceramide synthase (IPCS) has emerged as an important, interesting and attractive target in the sphingolipid metabolism of Leishmania. IPCS catalyzes the conversion of ceramide to IPC which forms the most predominant sphingolipid in Leishmania. IPCS has no mammalian equivalent and...

Descripción completa

Detalles Bibliográficos
Autores principales: Mandlik, Vineetha, Singh, Shailza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089144/
https://www.ncbi.nlm.nih.gov/pubmed/27853511
http://dx.doi.org/10.12688/f1000research.9151.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089144/
https://www.ncbi.nlm.nih.gov/pubmed/27853511
http://dx.doi.org/10.12688/f1000research.9151.2

Ejemplares similares