The Role of DNA Methylation in the Metabolic Memory Phenomenon Associated With the Continued Progression of Diabetic Retinopathy

PURPOSE: Clinical and experimental studies have shown that diabetic retinopathy progression does not halt after termination of hyperglycemia, suggesting a “metabolic memory” phenomenon. DNA is highly dynamic, and cytosine methylation changes can last for several years. In diabetes, DNA methylation r...

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Detalles Bibliográficos
Autores principales: Mishra, Manish, Kowluru, Renu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089211/
https://www.ncbi.nlm.nih.gov/pubmed/27787562
http://dx.doi.org/10.1167/iovs.16-19759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089211/
https://www.ncbi.nlm.nih.gov/pubmed/27787562
http://dx.doi.org/10.1167/iovs.16-19759

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