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Identification and Functional Assessment of Age-Dependent Truncations to Cx46 and Cx50 in the Human Lens
PURPOSE: Many proteins in the lens undergo extensive posttranslational modifications (PTMs) with age, leading to alterations in their function. The extent to which lens gap junction proteins, Cx46 and Cx50, accumulate PTMs with aging is not known. In this study, we identified truncations in Cx46 and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089213/ https://www.ncbi.nlm.nih.gov/pubmed/27787559 http://dx.doi.org/10.1167/iovs.16-19698 |