Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β‐catenin signaling pathway after spinal cord injury

Statins exhibit neuroprotective effects after spinal cord injury (SCI). However, the molecular mechanism underlying these effects remains unknown. This study demonstrates that the hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin (Simv) exhibits neuroprotective effects on neuronal apo...

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Detalles Bibliográficos
Autores principales: Gao, Kai, Shen, Zhaoliang, Yuan, Yajiang, Han, Donghe, Song, Changwei, Guo, Yue, Mei, Xifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089634/
https://www.ncbi.nlm.nih.gov/pubmed/26443048
http://dx.doi.org/10.1111/jnc.13382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089634/
https://www.ncbi.nlm.nih.gov/pubmed/26443048
http://dx.doi.org/10.1111/jnc.13382

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