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Downregulation of CXCR4 Expression and Functionality After Zoledronate Exposure in Canine Osteosarcoma

BACKGROUND: The establishment and progression of metastases remains the life‐limiting factor for dogs diagnosed with osteosarcoma (OS). The pattern of metastases is likely regulated through interactions between chemokine receptors and chemokines, and perturbations in these signaling cascades respons...

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Detalles Bibliográficos
Autores principales: Byrum, M.L., Pondenis, H.C., Fredrickson, R.L., Wycislo, K.L., Fan, T.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089657/
https://www.ncbi.nlm.nih.gov/pubmed/27251585
http://dx.doi.org/10.1111/jvim.14257