Acute Malaria Induces PD1(+)CTLA4(+) Effector T Cells with Cell-Extrinsic Suppressor Function

In acute Plasmodium falciparum (P. falciparum) malaria, the pro- and anti-inflammatory immune pathways must be delicately balanced so that the parasitemia is controlled without inducing immunopathology. An important mechanism to fine-tune T cell responses in the periphery is the induction of coinhib...

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Detalles Bibliográficos
Autores principales: Mackroth, Maria Sophia, Abel, Annemieke, Steeg, Christiane, Schulze zur Wiesch, Julian, Jacobs, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089727/
https://www.ncbi.nlm.nih.gov/pubmed/27802341
http://dx.doi.org/10.1371/journal.ppat.1005909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089727/
https://www.ncbi.nlm.nih.gov/pubmed/27802341
http://dx.doi.org/10.1371/journal.ppat.1005909

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