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Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline

Ciliopathies represent a broad class of disorders that affect multiple organ systems. The craniofacial complex is among those most severely affected when primary cilia are not functional. We previously reported that loss of primary cilia on cranial neural crest cells, via a conditional knockout of t...

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Detalles Bibliográficos
Autores principales: Chang, Ching-Fang, Chang, Ya-Ting, Millington, Grethel, Brugmann, Samantha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089743/
https://www.ncbi.nlm.nih.gov/pubmed/27802276
http://dx.doi.org/10.1371/journal.pgen.1006351