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Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline
Ciliopathies represent a broad class of disorders that affect multiple organ systems. The craniofacial complex is among those most severely affected when primary cilia are not functional. We previously reported that loss of primary cilia on cranial neural crest cells, via a conditional knockout of t...
Autores principales: | Chang, Ching-Fang, Chang, Ya-Ting, Millington, Grethel, Brugmann, Samantha A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089743/ https://www.ncbi.nlm.nih.gov/pubmed/27802276 http://dx.doi.org/10.1371/journal.pgen.1006351 |
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