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Raspberry-like poly(γ-glutamic acid) hydrogel particles for pH-dependent cell membrane passage and controlled cytosolic delivery of antitumor drugs

In this research, we synthesized bioderived poly(amino acid) hydrogel particles that showed pH-dependent membrane-disrupting properties and controlled cytosolic delivery of antitumor drugs. Poly(γ-glutamic acid) (γ-PGA) that has been produced extensively using bacteria, especially those of Bacillus...

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Detalles Bibliográficos
Autores principales: Cho, Sun-Hee, Hong, Ji Hyeon, Noh, Young-Woock, Lee, Eunji, Lee, Chang-Soo, Lim, Yong Taik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089826/
https://www.ncbi.nlm.nih.gov/pubmed/27822040
http://dx.doi.org/10.2147/IJN.S117862