Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

The target of β-lactam antibiotics is the D,D-transpeptidase activity of penicillin-binding proteins (PBPs) for synthesis of 4→3 cross-links in the peptidoglycan of bacterial cell walls. Unusual 3→3 cross-links formed by L,D-transpeptidases were first detected in Escherichia coli more than four deca...

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Detalles Bibliográficos
Autores principales: Hugonnet, Jean-Emmanuel, Mengin-Lecreulx, Dominique, Monton, Alejandro, den Blaauwen, Tanneke, Carbonnelle, Etienne, Veckerlé, Carole, Brun, Yves, V., van Nieuwenhze, Michael, Bouchier, Christiane, Tu, Kuyek, Rice, Louis B, Arthur, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089857/
https://www.ncbi.nlm.nih.gov/pubmed/27767957
http://dx.doi.org/10.7554/eLife.19469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089857/
https://www.ncbi.nlm.nih.gov/pubmed/27767957
http://dx.doi.org/10.7554/eLife.19469

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