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Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes

Endosomal membrane trafficking requires coordination between phosphoinositide lipids, Rab GTPases, and microtubule-based motors to dynamically determine endosome identity and promote long-range organelle transport. Here we report that ankyrin-B (AnkB), through integrating all three systems, function...

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Detalles Bibliográficos
Autores principales: Qu, Fangfei, Lorenzo, Damaris N, King, Samantha J, Brooks, Rebecca, Bear, James E, Bennett, Vann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089861/
https://www.ncbi.nlm.nih.gov/pubmed/27718357
http://dx.doi.org/10.7554/eLife.20417