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Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes
Endosomal membrane trafficking requires coordination between phosphoinositide lipids, Rab GTPases, and microtubule-based motors to dynamically determine endosome identity and promote long-range organelle transport. Here we report that ankyrin-B (AnkB), through integrating all three systems, function...
Autores principales: | Qu, Fangfei, Lorenzo, Damaris N, King, Samantha J, Brooks, Rebecca, Bear, James E, Bennett, Vann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089861/ https://www.ncbi.nlm.nih.gov/pubmed/27718357 http://dx.doi.org/10.7554/eLife.20417 |
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