ROCK1 Is Associated with Alzheimer’s Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic Aβ Clearance

Alzheimer’s disease (AD) is the most prevalent form of late-life dementia in the population, characterized by amyloid plaque formation and increased tau deposition, which is modulated by Rho-associated coiled-coil kinase 1 (ROCK1). In this study, we further analyze whether ROCK1 regulates the metabo...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yong-Bo, Zou, Yang, Huang, Yue, Zhang, Yong-Fang, Lourenco, Guinevere F., Chen, Sheng-Di, Halliday, Glenda M., Wang, Gang, Ren, Ru-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089992/
https://www.ncbi.nlm.nih.gov/pubmed/27853422
http://dx.doi.org/10.3389/fncel.2016.00253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089992/
https://www.ncbi.nlm.nih.gov/pubmed/27853422
http://dx.doi.org/10.3389/fncel.2016.00253

Ejemplares similares