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Exogenous Activation of Invariant Natural Killer T Cells by α-Galactosylceramide Reduces Pneumococcal Outgrowth and Dissemination Postinfluenza

Influenza A virus infection can predispose to potentially devastating secondary bacterial infections. Invariant natural killer T (iNKT) cells are unconventional, lipid-reactive T lymphocytes that exert potent immunostimulatory functions. Using a mouse model of postinfluenza invasive secondary pneumo...

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Detalles Bibliográficos
Autores principales: Barthelemy, Adeline, Ivanov, Stoyan, Hassane, Maya, Fontaine, Josette, Heurtault, Béatrice, Frisch, Benoit, Faveeuw, Christelle, Paget, Christophe, Trottein, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090038/
https://www.ncbi.nlm.nih.gov/pubmed/27803187
http://dx.doi.org/10.1128/mBio.01440-16