Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis

Identification and annotation of functional residues are fundamental questions in protein sequence analysis. Sequence and structure conservation provides valuable information to tackle these questions. It is, however, limited by the incomplete sampling of sequence space in natural evolution. Moreove...

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Detalles Bibliográficos
Autores principales: Du, Yushen, Wu, Nicholas C., Jiang, Lin, Zhang, Tianhao, Gong, Danyang, Shu, Sara, Wu, Ting-Ting, Sun, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090041/
https://www.ncbi.nlm.nih.gov/pubmed/27803181
http://dx.doi.org/10.1128/mBio.01801-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090041/
https://www.ncbi.nlm.nih.gov/pubmed/27803181
http://dx.doi.org/10.1128/mBio.01801-16

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