Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele

Misfolding and aggregation of amyloid β (Aβ) are key features of Alzheimer's disease (AD) pathogenesis, but the molecular events controlling this process are not known in detail. In vivo, Aβ aggregation and plaque formation occur in the interstitial fluid of the brain extracellular matrix. This...

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Detalles Bibliográficos
Autores principales: Padayachee, E.R., Zetterberg, H., Portelius, E., Borén, J., Molinuevo, J.L., Andreasen, N., Cukalevski, R., Linse, S., Blennow, K., Andreasson, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2016
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090044/
https://www.ncbi.nlm.nih.gov/pubmed/27653981
http://dx.doi.org/10.1016/j.brainres.2016.09.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090044/
https://www.ncbi.nlm.nih.gov/pubmed/27653981
http://dx.doi.org/10.1016/j.brainres.2016.09.022

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