Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation

Oral squamous cell carcinoma (OSCC) is genetically highly heterogeneous, which contributes to the challenges of treatment. To create an in vitro model that accurately reflects this heterogeneity, we generated a panel of HPV-negative OSCC cell lines. By whole exome sequencing of the lines and matched...

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Detalles Bibliográficos
Autores principales: Hayes, Tyler F., Benaich, Nathan, Goldie, Stephen J., Sipilä, Kalle, Ames-Draycott, Ashley, Cai, Wenjun, Yin, Guangliang, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090049/
https://www.ncbi.nlm.nih.gov/pubmed/27693639
http://dx.doi.org/10.1016/j.canlet.2016.09.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090049/
https://www.ncbi.nlm.nih.gov/pubmed/27693639
http://dx.doi.org/10.1016/j.canlet.2016.09.014

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