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Disease implication of hyper-Hippo signalling

The Hippo signalling pathway regulates cellular proliferation, apoptosis and differentiation, thus exerting profound effects on cellular homeostasis. Inhibition of Hippo signalling has been frequently implicated in human cancers, indicating a well-known tumour suppressor function of the Hippo pathwa...

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Detalles Bibliográficos
Autores principales: Wang, Shu-Ping, Wang, Lan-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090056/
https://www.ncbi.nlm.nih.gov/pubmed/27805903
http://dx.doi.org/10.1098/rsob.160119