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The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition

Kinesins that influence the dynamics of microtubule growth and shrinkage require the ability to distinguish between the microtubule end and the microtubule lattice. The microtubule depolymerizing kinesin MCAK has been shown to specifically recognize the microtubule end. This ability is key to the ac...

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Detalles Bibliográficos
Autores principales: Patel, Jennifer T., Belsham, Hannah R., Rathbone, Alexandra J., Wickstead, Bill, Gell, Christopher, Friel, Claire T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090061/
https://www.ncbi.nlm.nih.gov/pubmed/27733589
http://dx.doi.org/10.1098/rsob.160223