Cargando…
The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition
Kinesins that influence the dynamics of microtubule growth and shrinkage require the ability to distinguish between the microtubule end and the microtubule lattice. The microtubule depolymerizing kinesin MCAK has been shown to specifically recognize the microtubule end. This ability is key to the ac...
Autores principales: | Patel, Jennifer T., Belsham, Hannah R., Rathbone, Alexandra J., Wickstead, Bill, Gell, Christopher, Friel, Claire T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090061/ https://www.ncbi.nlm.nih.gov/pubmed/27733589 http://dx.doi.org/10.1098/rsob.160223 |
Ejemplares similares
-
A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition
por: Belsham, Hannah R., et al.
Publicado: (2017) -
A synthetic ancestral kinesin-13 depolymerizes microtubules faster than any natural depolymerizing kinesin
por: Belsham, Hannah R., et al.
Publicado: (2022) -
The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization
por: Friel, Claire T, et al.
Publicado: (2011) -
Identification of key residues that regulate the interaction of kinesins with microtubule ends
por: Belsham, Hannah R., et al.
Publicado: (2019) -
Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK
por: Shrestha, Roshan L., et al.
Publicado: (2013)