Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set

To assess the statistical significance of associations between variants and traits, genome-wide association studies (GWAS) should employ an appropriate threshold that accounts for the massive burden of multiple testing in the study. Although most studies in the current literature commonly set a geno...

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Detalles Bibliográficos
Autores principales: Kanai, Masahiro, Tanaka, Toshihiro, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090169/
https://www.ncbi.nlm.nih.gov/pubmed/27305981
http://dx.doi.org/10.1038/jhg.2016.72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090169/
https://www.ncbi.nlm.nih.gov/pubmed/27305981
http://dx.doi.org/10.1038/jhg.2016.72

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