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Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set
To assess the statistical significance of associations between variants and traits, genome-wide association studies (GWAS) should employ an appropriate threshold that accounts for the massive burden of multiple testing in the study. Although most studies in the current literature commonly set a geno...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090169/ https://www.ncbi.nlm.nih.gov/pubmed/27305981 http://dx.doi.org/10.1038/jhg.2016.72 |