Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer’s Disease

Fluselenamyl (5), a novel planar benzoselenazole shows traits desirable of enabling noninvasive imaging of Aβ pathophysiology in vivo; labeling of both diffuse (an earlier manifestation of neuritic plaques) and fibrillar plaques in Alzheimer’s disease (AD) brain sections, and remarkable specificity...

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Detalles Bibliográficos
Autores principales: Sundaram, G. S. M., Dhavale, Dhruva D., Prior, Julie L., Yan, Ping, Cirrito, John, Rath, Nigam P., Laforest, Richard, Cairns, Nigel J., Lee, Jin-Moo, Kotzbauer, Paul T., Sharma, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090206/
https://www.ncbi.nlm.nih.gov/pubmed/27805057
http://dx.doi.org/10.1038/srep35636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090206/
https://www.ncbi.nlm.nih.gov/pubmed/27805057
http://dx.doi.org/10.1038/srep35636

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