Cargando…

Molecular requirements of the B‐cell antigen receptor for sensing monovalent antigens

How the B‐cell antigen receptor (BCR) is activated upon interaction with its cognate antigen or with anti‐BCR antibodies is not fully understood. We have recently shown that B‐cell activation is accompanied by the opening of the pre‐organized BCR oligomers, an observation that strengthens the role o...

Descripción completa

Detalles Bibliográficos
Autores principales: Volkmann, Christoph, Brings, Naema, Becker, Martin, Hobeika, Elias, Yang, Jianying, Reth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090217/
https://www.ncbi.nlm.nih.gov/pubmed/27634959
http://dx.doi.org/10.15252/embj.201694177