Coenzyme Engineering of a Hyperthermophilic 6-Phosphogluconate Dehydrogenase from NADP(+) to NAD(+) with Its Application to Biobatteries

Engineering the coenzyme specificity of redox enzymes plays an important role in metabolic engineering, synthetic biology, and biocatalysis, but it has rarely been applied to bioelectrochemistry. Here we develop a rational design strategy to change the coenzyme specificity of 6-phosphogluconate dehy...

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Detalles Bibliográficos
Autores principales: Chen, Hui, Zhu, Zhiguang, Huang, Rui, Zhang, Yi-Heng Percival
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090862/
https://www.ncbi.nlm.nih.gov/pubmed/27805055
http://dx.doi.org/10.1038/srep36311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090862/
https://www.ncbi.nlm.nih.gov/pubmed/27805055
http://dx.doi.org/10.1038/srep36311

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