Genome-wide analyses reveal a highly conserved Dengue virus envelope peptide which is critical for virus viability and antigenic in humans

Targeting regions of proteins that show a high degree of structural conservation has been proposed as a method of developing immunotherapies and vaccines that may bypass the wide genetic variability of RNA viruses. Despite several attempts, a vaccine that protects evenly against the four circulating...

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Detalles Bibliográficos
Autores principales: Fleith, Renata C., Lobo, Francisco P., dos Santos, Paula F., Rocha, Mariana M., Bordignon, Juliano, Strottmann, Daisy M., Patricio, Daniel O., Pavanelli, Wander R., Lo Sarzi, Maria, Santos, Claudia N. D., Ferguson, Brian J., Mansur, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090869/
https://www.ncbi.nlm.nih.gov/pubmed/27805018
http://dx.doi.org/10.1038/srep36339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090869/
https://www.ncbi.nlm.nih.gov/pubmed/27805018
http://dx.doi.org/10.1038/srep36339

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