Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis

Harmine is a natural compound possessing insulin-sensitizing effect in db/db diabetic mice. However its effect on adipose tissue browning is unknown. Here we reveal that harmine antagonizes high fat diet-induced adiposity. Harmine-treated mice gained less weight on a high fat diet and displayed incr...

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Detalles Bibliográficos
Autores principales: Nie, Tao, Hui, Xiaoyan, Mao, Liufeng, Nie, Baoming, Li, Kuai, Sun, Wei, Gao, Xuefei, Tang, Xiaofeng, Xu, Yong, Jiang, Baishan, Tu, Zhengcao, Li, Peng, Ding, Ke, Han, Weiping, Zhang, Shaoping, Xu, Aimin, Ding, Sheng, Liu, Pentao, Patterson, Adam, Cooper, Garth, Wu, Donghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090989/
https://www.ncbi.nlm.nih.gov/pubmed/27805061
http://dx.doi.org/10.1038/srep36382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090989/
https://www.ncbi.nlm.nih.gov/pubmed/27805061
http://dx.doi.org/10.1038/srep36382

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